AST-1, a novel ETS-box transcription factor, controls axon guidance and pharynx development in C. elegans.

Abstract excerpt

Neurons send out axons and dendrites over large distances into target areas where they eventually form synapses with selected target cells. Axonal navigation is controlled by a variety of extracellular signals and neurons express receptors only for that subset of signals they need to navigate to their own target area. How the expression of axon guidance receptors is regulated is not understood. In genetic screens...

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