Article
Bone marrow-derived cells that populate the adult mouse brain preserve their hematopoietic identity.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jun 2003
Vallières Luc, Sawchenko Paul E
Abstract excerpt
Cytogenesis in the adult brain can result from the recruitment of circulating precursors, but the proposal that some such cells transdifferentiate into neural elements is controversial. We have reinvestigated this issue by following the phenotypic fate of bone marrow cells expressing the green fluorescent protein transplanted into the systemic circulation of irradiated mice. Thousands of donor-derived cells were...
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