Article
From marrow to brain: expression of neuronal phenotypes in adult mice.
Science (New York, N.Y.) - 1 Dec 2000
Brazelton T R, Rossi F M, Keshet G I, Blau H M
Abstract excerpt
After intravascular delivery of genetically marked adult mouse bone marrow into lethally irradiated normal adult hosts, donor-derived cells expressing neuronal proteins (neuronal phenotypes) developed in the central nervous system. Flow cytometry revealed a population of donor-derived cells in the brain with characteristics distinct from bone marrow. Confocal microscopy of individual cells showed that hundreds of...
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