Article
Evidence for non-random distribution of Fcgamma receptor genotype combinations.
Immunogenetics - 1 Jul 2003
van der Pol W-Ludo, Jansen Marc D, Sluiter Wim J, van de Sluis Bart, Leppers-van de Straat Fredriek G J, Kobayashi Tetsuo, Westendorp Rudi G J, Huizinga Tom W J, van de Winkel Jan G J
Abstract excerpt
Human IgG receptors (FcgammaR) display considerable heterogeneity, and are crucial immune response modulating molecules. FcgammaRIIA, FcgammaRIIIA, and FcgammaRIIIB display functional biallelic polymorphisms. FcgammaR polymorphisms have been found associated with susceptibility to infectious and autoimmune diseases. Linked transmission of FcgammaR alleles was studied by determining the distribution of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
