Article
Both risk alleles for FcgammaRIIA and FcgammaRIIIA are susceptibility factors for SLE: a unifying hypothesis.
Genes and immunity - 1 Mar 2004
Magnusson V, Johanneson B, Lima G, Odeberg J, Alarcón-Segovia D, Alarcón-Riquelme M E
Abstract excerpt
The aim of this study was to analyze in families with SLE for the presence of linkage and the structure and transmission of haplotypes containing alleles for the low-affinity Fcgamma receptors. The Fcgamma receptor polymorphisms FcgammaRIIA-131R/H, FcgammaRIIIA-176F/V and FcgammaRIIIB-NA1/2 and a polymorphism in the FcgammaRIIB gene were genotyped with RFLP, allele-specific PCR or pyrosequencing. Individual SNPs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
