Article
Genetic linkage and association of Fcgamma receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus.
Arthritis and rheumatism - 1 Aug 2002
Edberg Jeffrey C, Langefeld Carl D, Wu Jianming, Moser Kathy L, Kaufman Kenneth M, Kelly Jennifer, Bansal Vipin, Brown W Mark, Salmon Jane E, Rich Stephen S, Harley John B, Kimberly Robert P
Abstract excerpt
OBJECTIVE: Although low-affinity alleles of human Fcgamma receptor types IIA and IIIA (FcgammaRIIA and FcgammaRIIIA, respectively) polymorphisms have been associated with systemic lupus erythematosus (SLE) in case-control studies, the relative contribution of these genes to SLE susceptibility has not been resolved. METHODS: We analyzed the distribution of alleles of FcgammaRIIA, FcgammaRIIIA, and FcgammaRIIIB in...
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