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Article

Identification of the p16-Arc subunit of the Arp 2/3 complex as a substrate of MAPK-activated protein kinase 2 by proteomic analysis.

The Journal of biological chemistry - 19 Sept 2003

Singh Saurabh, Powell David W, Rane Madhavi J, Millard Tom H, Trent John O, Pierce William M, Klein Jon B, Machesky Laura M, McLeish Kenneth R

Abstract excerpt

The p38 MAPK pathway regulates multiple neutrophil functional responses via activation of the serine-threonine kinase MAPK-activated protein kinase 2 (MAPKAPK2). To identify substrates of MAPKAPK2 that mediate these responses, a proteomic approach was used in which in vitro phosphorylation of neu...

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Source

Identifiers

PMID: 12829704
DOI: 10.1074/jbc.M306428200

Genes

MAPKAPK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12829704-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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