Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasminogen supports tumor growth through a fibrinogen-dependent mechanism linked to vascular patency.

Blood - 15 Oct 2003

Palumbo Joseph S, Talmage Kathryn E, Liu Hong, La Jeunesse Christine M, Witte David P, Degen Jay L

Abstract excerpt

The growth of Lewis lung carcinoma (LLC) was sustained in plasminogen-deficient mice when transplanted into the dorsal skin but was dramatically suppressed in another anatomic location, the footpad. This unanticipated negative effect of plasminogen deficiency on footpad tumor growth was entirely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibrinogen
Share to Fibrosarcoma
Share to Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Electron

Share to Mitosis

Share to Neoplasm Transplantation

Share to Neoplasms

Share to Plasminogen

Source

Identifiers

PMID: 12829586
DOI: 10.1182/blood-2003-03-0881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12829586-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasminogen supports tumor growth through a fibrinogen-dependent mechanism linked to vascular patency.PMID 12829586Read ↗

Plasminogen receptor S100A10 is essential for the migration of tumor-promoting macrophages into tumor sites.Semantic proximity Read ↗

Structure and function of the plasminogen/plasmin system.Semantic proximity Read ↗

Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner.Semantic proximity Read ↗

Direct evidence of the importance of stromal urokinase plasminogen activator (uPA) in the growth of an experimental human breast cancer using a combined uPA gene-disrupted and immunodeficient xenograft model.Semantic proximity Read ↗

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.Semantic proximity Read ↗

The urokinase-type plasminogen activator system in cancer metastasis: A reviewSemantic proximity Read ↗

Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.Semantic proximity Read ↗

The role of plasminogen in angiogenesis in vivo.Semantic proximity Read ↗

Influence of plasminogen deficiency on the contribution of polymorphonuclear leucocytes to fibrin/ogenolysis: studies in plasminogen knock-out mice.Semantic proximity Read ↗

Phenotypic properties of herpesvirus-transformed cells with high tumorigenic and metastatic ability.Semantic proximity Read ↗

Expression of recombinant human plasminogen in mammalian cells is augmented by suppression of plasmin activity.Semantic proximity Read ↗

Plasmin modulates vascular endothelial growth factor-A-mediated angiogenesis during wound repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.