Article
IL-1RN VNTR polymorphism and genetic susceptibility to cervical cancer in Portugal.
Molecular biology reports - 1 Dec 2012
Sousa Hugo, Santos Alexandra M, Catarino Raquel, Pinto Daniela, Moutinho José, Canedo Paulo, Machado José Carlos, Medeiros Rui
Abstract excerpt
Human Papillomavirus infection is considered as the main etiological factor of cervical cancer (ICC), although, the role of host genetic factors in ICC susceptibility has been increasing. Immunological response is crucial for the prevention of viral associated diseases. Interleukin 1 receptor antagonist (IL-1RN) is considered to be an important regulator of host immunity and several studies have shown a potential...
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