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Article

Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.

AIDS (London, England) - 23 May 2003

Matsumi Shintaro, Kosalaraksa Pope, Tsang Hsinyi, Kavlick Mark F, Harada Shigeyoshi, Mitsuya Hiroaki

Abstract excerpt

OBJECTIVE: To investigate the mechanism by which the Q151M mutation in reverse transcriptase (RT) that confers multi-dideoxynucleoside resistance on HIV-1 and that requires a two base change (CAG-->ATG) develops, and to understand the reason for the relatively lengthy period of time required for its emergence under therapy with multiple nucleoside RT inhibitors (NRTI). DESIGN AND METHODS: Propagation assays and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12819513
DOI: 10.1097/00002030-200305230-00003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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