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Article

Comparative fitness of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 (HIV-1) in an In vitro competitive HIV-1 replication assay.

Journal of virology - 1 Jul 1999

Kosalaraksa P, Kavlick M F, Maroun V, Le R, Mitsuya H

Abstract excerpt

We examined whether human immunodeficiency virus type 1 (HIV-1) fitness was altered upon the acquisition of a set or subset of five mutations (A62V, V75I, F77L, F116Y, and Q151M) in the pol gene, which confers resistance to multiple dideoxynucleosides (MDR), as well as the zidovudine resistance-associated mutation T215Y, using a competitive HIV-1 replication assay in a setting of an HXB2D genetic background....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10364282
DOI: 10.1128/JVI.73.7.5356-5363.1999
PMCID: PMC112591

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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