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Article

Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2003

Tharaux Pierre-Louis, Bukoski Richard C, Rocha Paulo N, Crowley Steven D, Ruiz Phillip, Nataraj Chandra, Howell David N, Kaibuchi Kozo, Spurney Robert F, Coffman Thomas M

Abstract excerpt

Coordinated rearrangements of the actin-myosin cytoskeleton facilitate early and late events in T cell activation and signal transduction. As many important features of cell shape rearrangement involve small GTP-binding proteins, we examined the contribution of Rho kinase to the functions of matu...

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Identifiers

PMID: 12816987
DOI: 10.4049/jimmunol.171.1.96

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12816987-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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