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Article

RhoG regulates gene expression and the actin cytoskeleton in lymphocytes.

Oncogene - 23 Jan 2003

Vigorito Elena, Billadeu Daniel D, Savoy Doris, McAdam Simon, Doody Gina, Fort Phillipe, Turner Martin

Abstract excerpt

RhoG, a member of the Rho family of GTPases, has been implicated as a regulator of the actin cytoskeleton. In this study, we show a novel function for the small GTPase RhoG on the regulation of the interferon-gamma promoter and nuclear factor of activated T cells (NFAT) gene transcription in lymphocytes. Optimal function of RhoG for the expression of these genes requires a calcium signal, normally provided by the...

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Source

Identifiers

PMID: 12545154
DOI: 10.1038/sj.onc.1206116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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