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Article

Immunological function in mice lacking the Rac-related GTPase RhoG.

Molecular and cellular biology - 1 Jan 2004

Vigorito Elena, Bell Sarah, Hebeis Barbara J, Reynolds Helen, McAdam Simon, Emson Piers C, McKenzie Andrew, Turner Martin

Abstract excerpt

RhoG is a low-molecular-weight GTPase highly expressed in lymphocytes that activates gene transcription and promotes cytoskeletal reorganization in vitro. To study the in vivo function of RhoG, we generated mice homozygous for a targeted disruption of the RhoG gene. Despite the absence of RhoG, t...

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Identifiers

PMID: 14701744
DOI: 10.1128/MCB.24.2.719-729.2004
PMCID: PMC343784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14701744-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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