Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome wide scan using homozygosity mapping and linkage analyses of a single pedigree with affective disorder suggests oligogenic inheritance.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2003

Ewald Henrik, Kruse Torben A, Mors Ole

Abstract excerpt

The present study reports results from a genome scan on a family with bipolar affective disorder in which the parents are first cousins and four of the offsprings and one grandchild have affective disorder. The study searched for risk loci for affective disorder by searching for homozygous segments or more complex inherited loci using parametric and non-parametric multipoint linkage analysis. In addition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Chromosomes, Human, Pair 10

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 12

Share to Chromosomes, Human, Pair 2

Share to Chromosomes, Human, Pair 21

Share to Consanguinity

Share to Denmark

Share to Mood Disorders

Source

Identifiers

PMID: 12815742
DOI: 10.1002/ajmg.b.20039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome wide scan using homozygosity mapping and linkage analyses of a single pedigree with affective disorder suggests oligogenic inheritance.PMID 12815742Read ↗

A genome-wide search for risk genes using homozygosity mapping and microarrays with 1,494 single-nucleotide polymorphisms in 22 eastern Cuban families with bipolar disorder.Semantic proximity Read ↗

Full-genome scan for linkage in 50 families segregating the bipolar affective disease phenotype.Semantic proximity Read ↗

A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q.Semantic proximity Read ↗

Genome scans for susceptibility genes in bipolar affective disorder.Semantic proximity Read ↗

The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report.Semantic proximity Read ↗

Genome screen of 15 Australian bipolar affective disorder pedigrees supports previously identified loci for bipolar susceptibility genes.Semantic proximity Read ↗

A follow-up report of a genome search for affective disorder predisposition loci in the Old Order Amish.Semantic proximity Read ↗

Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14.Semantic proximity Read ↗

A possible susceptibility locus for bipolar affective disorder in chromosomal region 10q25--q26.Semantic proximity Read ↗

A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus.Semantic proximity Read ↗

Two-dimensional genome scan identifies multiple genetic interactions in bipolar affective disorder.Semantic proximity Read ↗

A susceptibility locus for bipolar affective disorder on chromosome 4q35.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.