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Article

Two-dimensional genome scan identifies multiple genetic interactions in bipolar affective disorder.

Biological psychiatry - 1 Mar 2010

Fullerton Janice M, Donald Jennifer A, Mitchell Philip B, Schofield Peter R

Abstract excerpt

BACKGROUND: Bipolar disorder is a highly heritable psychiatric condition, the etiology of which remains largely unknown despite extensive efforts to identify susceptibility genes. Interactions between genes of small individual effect could partially explain the difficulties of traditional one-dimensional approaches to identify genetic risk factors. METHODS: A nonparametric linkage (NPL) analysis of 65 Australian...

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PMID: 20022591
DOI: 10.1016/j.biopsych.2009.10.022

Genes

NPL

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Source receipt: pubmed, retrieved 7 Sept 2026.

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