Article
The association between polymorphisms in glutathione S-transferase (GSTM1 and GSTT1) and lung cancer outcome.
Cancer investigation - 1 Jan 2000
Gonlugur Ugur, Pinarbasi Hatice, Gonlugur Tanseli Efeoglu, Silig Yavuz
Abstract excerpt
BACKGROUND: Polymorphisms in the glutathione S-transferase (GST) family may be associated with increased risk of lung cancer, somatic changes in lung tumour tissue, and survival. We evaluated survival according to GST polymorphism in lung cancer patients. METHODS: We studied DNA polymorphisms of 81 primary lung cancer patients at 2 glutathione-related loci: GSTM1, and GSTT1 that encode glutathione...
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