Article
Glutathione S-transferase T1 and M1 polymorphisms are associated with lung cancer risk in a gender-specific manner.
Oncology research and treatment - 1 Jan 2014
Pan Chunguo, Zhu Genhua, Yan Zhihong, Zhou Yi, Liu Zhihua
Abstract excerpt
BACKGROUND: Glutathione S-transferase (GST) T1 and M1 are detoxification enzymes which neutralize various carcinogenic compounds. Polymorphisms of the GSTT1 and GSTM1 genes which encode the enzymes could be associated with cancer risk. PATIENTS AND METHODS: We investigated the association of GSTT1 and GSTM1 null polymorphisms with lung cancer risk in a tightly matched, considerably large sample in China....
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