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Article

Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2010

Moyer Ann M, Sun Zhifu, Batzler Anthony J, Li Liang, Schaid Daniel J, Yang Ping, Weinshilboum Richard M

Abstract excerpt

BACKGROUND: Lung cancer is commonly treated with platinum compounds. The "glutathione pathway" participates in the metabolism of platinum compounds. We set out to test the hypotheses that single nucleotide polymorphisms (SNPs) or copy number polymorphisms for genes within the glutathione pathway...

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Source

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Identifiers

PMID: 20200426
DOI: 10.1158/1055-9965.EPI-09-0871
PMCID: PMC2837367

Genes

GSTM4
GSTT1
ABCC4
GSTA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20200426-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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