Article
Deletion of GSTM1 and GSTT1 genes and lung cancer survival: a systematic review.
Tumori - 31 Jul 2017
Ramos Hernández Cristina, Mouronte-Roibás Cecilia, Barros-Dios Juan Miguel, Fernández-Villar Alberto, Ruano-Ravina Alberto
Abstract excerpt
PURPOSE: The mechanisms of lung carcinogenesis are not fully understood. Not all smokers develop lung cancer, indicating that genetic variations and other environmental factors may play an important role in its development. The human glutathione S-transferases (GSTs) have been associated with an increased risk of lung cancer. Glutathione S-transferases are phase II biotransformation enzymes that play a role in...
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