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Article

Genetic determinants of lung cancer short-term survival: the role of glutathione-related genes.

Lung cancer (Amsterdam, Netherlands) - 1 Mar 2002

Yang Ping, Yokomizo Akira, Tazelaar Henry D, Marks Randolph S, Lesnick Timothy G, Miller Daniel L, Sloan Jeff A, Edell Eric S, Meyer Rebecca L, Jett James, Liu Wanguo

Abstract excerpt

PURPOSE: Survival of lung cancer patients has been dismal. Glutathione enzymes are directly involved in the metabolism of platinum compounds, a group of important chemotherapeutic drugs in cancer treatment. We tested the hypothesis that genes encoding glutathione enzymes may predict lung cancer short-term survival. METHODS: We studied DNA polymorphisms of 250 primary lung cancer patients at four...

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Source

Identifiers

PMID: 11844594
DOI: 10.1016/s0169-5002(01)00426-3

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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