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Cell cycle checkpoint revolution: targeted therapies in the fight against malignant tumors

11 Oct 2024

Abstract excerpt

Malignant tumors are among the most important causes of death worldwide. The pathogenesis of a malignant tumor is complex and has not been fully elucidated. Studies have shown that such pathogenesis is related to abnormal cell cycle progression. The expression levels of cyclins, cyclin-dependent kinases (CDKs), and CDK inhibitors as well as functions of the cell cycle checkpoints determine whether the cell cycle...

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PMID: 39464635
DOI: 10.3389/fphar.2024.1459057

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