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Cyclin-dependent protein kinases and cell cycle regulation in biology and disease

12 Jan 2025

Abstract excerpt

Cyclin Dependent Kinases (CDKs) are closely connected to the regulation of cell cycle progression, having been first identified as the kinases able to drive cell division. In reality, the human genome contains 20 different CDKs, which can be divided in at least three different sub-family with different functions, mechanisms of regulation, expression patterns and subcellular localization. Most of these kinases...

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PMID: 39800748
DOI: 10.1038/s41392-024-02080-z

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