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Article

Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells.

Oncogene - 19 Jun 2003

Kim Tai Young, Jong Hyun-Soon, Song Sang-Hyun, Dimtchev Alexandre, Jeong Sook-Jung, Lee Jung Weon, Kim Tae-You, Kim Noe Kyeong, Jung Mira, Bang Yung-Jue

Abstract excerpt

DLC-1 (deleted in liver cancer) gene is frequently deleted in hepatocellular carcinoma. However, little is known about the genetic status and the expression of this gene in gastric cancer. In this study, Northern and Southern analysis showed that seven of nine human gastric cancer cell lines did not express DLC-1 mRNA, but contained the DLC-1 gene. To identify the mechanism of the loss of DLC-1 mRNA expression in...

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PMID: 12813468
DOI: 10.1038/sj.onc.1206573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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