Chromosomal localization of the protein tyrosine phosphatase G1 gene and characterization of the aberrant transcripts in human colon cancer cells.

doi:10.1016/0014-5793(94)80420-6

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Article

Chromosomal localization of the protein tyrosine phosphatase G1 gene and characterization of the aberrant transcripts in human colon cancer cells.

FEBS letters - 21 Feb 1994

Takekawa M, Itoh F, Hinoda Y, Adachi M, Ariyama T, Inazawa J, Imai K, Yachi A

Abstract excerpt

We have recently described the isolation of the human PTPG1 gene which encodes a member of intracellular protein tyrosine phosphatases that may be candidates for tumor suppressor genes. In order to investigate the abnormality of the PTPG1 transcript in various human cancer cell lines, we have analyzed the consensus catalytic region of PTPG1 cDNA, using the reverse transcription polymerase chain reaction. In a...

Topics

Amino Acid Sequence
Base Sequence
Blotting, Southern
Cell Line
Chromosome Mapping
Chromosomes, Human, Pair 7
Colonic Neoplasms
Genes, Tumor Suppressor
Humans
In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Point Mutation

Polymerase Chain Reaction

Protein Tyrosine Phosphatases

RNA Splicing

RNA-Directed DNA Polymerase

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 7509295
DOI: 10.1016/0014-5793(94)80420-6

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7509295-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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