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Article

The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.

Developmental biology - 1 Jan 2016

Birol Onur, Ohyama Takahiro, Edlund Renée K, Drakou Katerina, Georgiades Pantelis, Groves Andrew K

Abstract excerpt

The inner ear develops from the otic placode, one of the cranial placodes that arise from a region of ectoderm adjacent to the anterior neural plate called the pre-placodal domain. We have identified a Forkhead family transcription factor, Foxi3, that is expressed in the pre-placodal domain and down-regulated when the otic placode is induced. We now show that Foxi3 mutant mice do not form otic placodes as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26550799
DOI: 10.1016/j.ydbio.2015.09.022
PMCID: PMC4688051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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