Article
Multiple roles of Rev3, the catalytic subunit of polzeta in maintaining genome stability in vertebrates.
The EMBO journal - 16 Jun 2003
Sonoda Eiichiro, Okada Takashi, Zhao Guang Yu, Tateishi Satoshi, Araki Kasumi, Yamaizumi Masaru, Yagi Takashi, Verkaik Nicole S, van Gent Dik C, Takata Minoru, Takeda Shunichi
Abstract excerpt
Translesion DNA synthesis (TLS) and homologous DNA recombination (HR) are two major postreplicational repair (PRR) pathways. The REV3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase zeta, which is involved in mutagenic TLS. To investigate the role of REV3 in verte...
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