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Article

Monocyte chemoattractant protein-4 core promoter genetic variants: influence on YY-1 affinity and plasma levels.

American journal of respiratory cell and molecular biology - 1 Dec 2003

Kalayci Omer, Birben Esra, Wu Liqing, Oguma Tsuyoshi, Storm Van's Gravesande Karin, Subramaniam Venkat, Sheldon Holly K, Silverman Eric S, Lilly Craig M

Abstract excerpt

Monocyte chemoattractant protein-4 (MCP-4) is a CC chemokine implicated in the recruitment of eosinophils, monocytes, and T-lymphocytes in diseases of mucosal inflammation, including asthma. We tested the hypothesis that there is a genetic basis for differences in MCP-4 expression among individuals by evaluating the effects of core promoter variants on MCP-4 expression. We identified two single-nucleotide T-to-C...

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Identifiers

PMID: 12805085
DOI: 10.1165/rcmb.2003-0024OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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