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Article

Oct-1 is responsible for the C-33T polymorphism effect in the IL-4 promoter.

International journal of immunogenetics - 1 Feb 2010

Gervaziev Y V, Olenina L V, Krasotkina J V, Lupatov A Y, Mazurina S A, Gervazieva V B

Abstract excerpt

IL-4 is a pleiotropic immunoregulatory cytokine secreted by Th2 subset of CD4(+) Th cells. Several transcription factors (TFs) have been determined with various degrees of certainty to bind the IL-4 promoter and to regulate its expression in human. To investigate the mechanisms responsible for phenotypic effects of the C-33T IL-4 promoter polymorphism, we performed a search of TFs binding to this promoter locus...

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Identifiers

PMID: 19804407
DOI: 10.1111/j.1744-313X.2009.00883.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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