Article
Functional analysis of the promoter region of the human phosphotyrosine phosphatase activator gene: Yin Yang 1 is essential for core promoter activity.
The Biochemical journal - 15 Dec 1999
Janssens V, Van Hoof C, De Baere I, Merlevede W, Goris J
Abstract excerpt
The phosphotyrosine phosphatase activator (PTPA) has been isolated as an in vitro regulator of protein phosphatase 2A. Human PTPA is encoded by a single gene, the structure and chromosomal localization of which have been determined in our previous work. Here we describe the further isolation, sequencing and functional characterization of the PTPA promoter region. In agreement with its ubiquitous expression, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.