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Article

Production of mouse ES cells homozygous for Cdk5-phosphorylated site mutation in c-Src alleles.

Journal of biochemistry - 1 May 2003

Kato Goro, Maeda Shuichiro

Abstract excerpt

c-Src-null mutants have not provided a full understanding of the cellular functions of c-Src, reflecting the functional redundancy among Src family members. c-Src is phosphorylated by cyclin-dependent kinase 1 (Cdk1) and Cdk5 at Ser75 in the unique amino terminal c-Src-specific domain. The specific roles of c-Src may be assessed by establishing mouse embryonic stem (ES) cells homozygous for a point mutation at...

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Identifiers

PMID: 12801906
DOI: 10.1093/jb/mvg072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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