Article
Myeloperoxidase promoter region polymorphism and lung cancer risk.
Methods in molecular medicine - 1 Jan 2003
Wu Xifeng, Schabath Matthew B, Spitz Margaret R
Abstract excerpt
Historically, myeloperoxidase activity and subsequent production of hypochlorous acid has been associated with the killing of host-invading microorganisms (bacteria, viruses, and fungi). Currently, there is a wealth of evidence that the MPO polymorphism and enzyme activity is associated with a wide range of pathological and biological processes, including lung cancer carcinogenesis. Although the molecular...
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