Article
Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are associated with polycystic ovary syndrome.
Fertility and sterility - 1 Jun 2003
Korhonen Seija, Romppanen Eeva Liisa, Hiltunen Mikko, Helisalmi Seppo, Punnonen Kari, Hippeläinen Maritta, Heinonen Seppo
Abstract excerpt
OBJECTIVE: To determine whether genetic variability in the gene encoding microsomal epoxide hydrolase (EPHX) contributes to individual differences in susceptibility to the development of polycystic ovary syndrome (PCOS). DESIGN: Retrospective case-control study. SETTING: University-based clinic. PATIENT(S): One hundred twelve white women with PCOS and 115 healthy controls. INTERVENTION(S): None. MAIN OUTCOME...
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