Article
Microsomal epoxide hydrolase polymorphism and susceptibility to ovarian cancer.
Cancer letters - 8 Mar 2002
Baxter S W, Choong D Y H, Campbell I G
Abstract excerpt
Polymorphic variants of microsomal epoxide hydrolase (mEPHX) with altered enzyme activity have been associated with an increased risk for ovarian cancer. We assessed the frequency of exon 3 and exon 4 variants of mEPHX among 291 ovarian cancers and 257 controls from a UK-based population. The distribution of the exon 3 alleles among both the cancer and control groups was significantly different from that expected...
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