Article
A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia.
Journal of medical genetics - 1 Apr 2001
Zusterzeel P L, Peters W H, Visser W, Hermsen K J, Roelofs H M, Steegers E A
Abstract excerpt
OBJECTIVE: Microsomal epoxide hydrolase is an important enzyme involved in the metabolism of endogenous and exogenous toxicants. Polymorphic variants of the human epoxide hydrolase gene vary in enzyme activity. We determined whether genetic variability in the gene encoding for microsomal epoxide hydrolase contributes to individual differences in susceptibility to the development of pre-eclampsia with or without...
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