Article
The microsomal epoxide hydrolase Tyr113His polymorphism: association with risk of ovarian cancer.
Molecular carcinogenesis - 1 Jan 2001
Spurdle A B, Purdie D M, Webb P M, Chen X, Green A, Chenevix-Trench G
Abstract excerpt
Functional significance has been demonstrated in vitro for the exon 3 T-->C Tyr113His amino acid substitution polymorphism of the microsomal epoxide hydrolase (EPHX) gene. The higher activity or fast TT genotype was previously reported to be associated with an increased risk of ovarian cancer, an...
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