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TP53 mutations in primary breast carcinomas from white and African-Brazilian patients.

International journal of oncology - 1 Jul 2003

Nagai Maria Aparecida, Schaer Barbosa Helenemarie, Zago Marco Antonio, Araújo Silva Wilson, Nishimoto Inês Nobuko, Salaorni Sibeli, Guerreiro Costa Lívia Nery Franco, Silva Araújo Marcos, Caldas Oliveira Ana Gabriela, Mourâo Neto Mário, Brentani Maria Mitzi

Abstract excerpt

We have attempted to determine the incidence, nature and clinical significance of TP53 mutation in a group of white (242 cases) and African-Brazilian (52 cases) patients with breast cancer. The interethnic admixture as estimated by STR markers showed that white subjects displayed 67.9+/-0.4%, 25.0+/-1.7% and 7.0%+/-1.6% and the black populations had 34.4+/-1.9%, 56.2+/-1.9 and 9.4+/-2.2% respectively of European,...

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PMID: 12792793

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