Article
Genetic variation in receptor protein tyrosine phosphatase sigma is associated with type 2 diabetes in Swedish Caucasians.
European journal of endocrinology - 1 Oct 2007
Långberg Ewa-Carin, Gu Harvest F, Nordman Sofia, Efendic Suad, Ostenson Claes-Göran
Abstract excerpt
OBJECTIVE: Previously, it has been demonstrated that receptor protein tyrosine phosphatase sigma (RPTPsigma) is involved in glucose homeostasis and insulin signaling in several animal models. The aim of this study was to evaluate whether polymorphisms in this gene influence the development of type 2 diabetes (T2D) in humans. DESIGN: We investigated how genetic variations in the RPTPsigma gene influence...
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