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Article

Splits ends is a tissue/promoter specific regulator of Wingless signaling.

Development (Cambridge, England) - 1 Jul 2003

Lin Hua V, Doroquez David B, Cho Soochin, Chen Fangli, Rebay Ilaria, Cadigan Ken M

Abstract excerpt

Wingless directs many developmental processes in Drosophila by regulating expression of specific target genes through a conserved signaling pathway. Although many nuclear factors have been implicated in mediating Wingless-induced transcription, the mechanism of how Wingless regulates different targets in different tissues remains poorly understood. We report here that the split ends gene is required for Wingless...

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PMID: 12783785
DOI: 10.1242/dev.00527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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