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Article

Mutagenesis screens for interacting genes reveal three roles for fat facets during Drosophila eye development.

Developmental genetics - 1 Jan 1997

Fischer J A, Leavell S K, Li Q

Abstract excerpt

The Drosophila fat facets gene encodes a deubiquitinating enzyme that regulates a cell communication pathway essential early during eye development to inhibit the determination of excess photoreceptors. Ubiquitin is a small polypeptide that tags proteins for degradation by a multisubunit proteolytic complex called the proteasome. The FAT FACETS protein is thought to be required to remove ubiquitin from a...

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PMID: 9332974
DOI: 10.1002/(SICI)1520-6408(1997)21:2<167::AID-DVG6>3.0.CO;2-5

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Mutagenesis screens for interacting genes reveal three roles for fat facets during Drosophila eye development.PMID 9332974Read ↗

Genetic analysis of the role of the drosophila fat facets gene in the ubiquitin pathway.Semantic proximity Read ↗

Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets deubiquitinating enzyme in Drosophila eye development.Semantic proximity Read ↗

In vivo Structure/Function analysis of the Drosophila fat facets deubiquitinating enzyme gene.Semantic proximity Read ↗

The function of the Drosophila fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis.Semantic proximity Read ↗

The deubiquitination enzyme fat facets negatively regulates RTK/Ras/MAPK signalling during Drosophila eye development.Semantic proximity Read ↗

Identification of genes that interact with Drosophila liquid facets.Semantic proximity Read ↗

Keeping an eye on the fly genome.Semantic proximity Read ↗

Eye development.Semantic proximity Read ↗

fat facets induces polyubiquitination of Imd and inhibits the innate immune response in Drosophila.Semantic proximity Read ↗

A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila.Semantic proximity Read ↗

Control of protein degradation by E3 ubiquitin ligases in Drosophila eye developmentSemantic proximity Read ↗

Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.Semantic proximity Read ↗

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