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Article

Mutagenesis screens for interacting genes reveal three roles for fat facets during Drosophila eye development.

Developmental genetics - 1 Jan 1997

Fischer J A, Leavell S K, Li Q

Abstract excerpt

The Drosophila fat facets gene encodes a deubiquitinating enzyme that regulates a cell communication pathway essential early during eye development to inhibit the determination of excess photoreceptors. Ubiquitin is a small polypeptide that tags proteins for degradation by a multisubunit proteoly...

Topics

Animals
Drosophila
Endopeptidases
Eye
Genes, Dominant
Genes, Insect
Genetic Complementation Test
Homozygote
Male
Mutagenesis
Mutation
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9332974
DOI: 10.1002/(SICI)1520-6408(1997)21:2<167::AID-DVG6>3.0.CO;2-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9332974-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mutagenesis screens for interacting genes reveal three roles for fat facets during Drosophila eye development.PMID 9332974Read ↗

Genetic analysis of the role of the drosophila fat facets gene in the ubiquitin pathway.Semantic proximity Read ↗

Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets deubiquitinating enzyme in Drosophila eye development.Semantic proximity Read ↗

In vivo Structure/Function analysis of the Drosophila fat facets deubiquitinating enzyme gene.Semantic proximity Read ↗

The function of the Drosophila fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis.Semantic proximity Read ↗

The deubiquitination enzyme fat facets negatively regulates RTK/Ras/MAPK signalling during Drosophila eye development.Semantic proximity Read ↗

Identification of genes that interact with Drosophila liquid facets.Semantic proximity Read ↗

Keeping an eye on the fly genome.Semantic proximity Read ↗

Eye development.Semantic proximity Read ↗

fat facets induces polyubiquitination of Imd and inhibits the innate immune response in Drosophila.Semantic proximity Read ↗

A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila.Semantic proximity Read ↗

Control of protein degradation by E3 ubiquitin ligases in Drosophila eye developmentSemantic proximity Read ↗

Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.Semantic proximity Read ↗

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