Article
ERECT WING, the Drosophila member of a family of DNA binding proteins is required in imaginal myoblasts for flight muscle development.
Development (Cambridge, England) - 1 Jan 1996
DeSimone S, Coelho C, Roy S, VijayRaghavan K, White K
Abstract excerpt
The erect wing locus of the fruit fly Drosophila melanogaster encodes a protein, EWG, that shares extensive homology with the P3A2 DNA binding protein of sea urchin and a recently identified mammalian transcription factor. Loss-of-function erect wing alleles result in embryonic lethality. Viable...
Topics
- Animals
- Animals, Genetically Modified
- Crosses, Genetic
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Flight, Animal
- Gene Expression Regulation, Developmental
- Genes, Insect
- Male
- Muscle Development
- Muscle, Skeletal
- Mutation
- Nervous System
- Neuropeptides
- Nuclear Proteins
- Phenotype