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Article

NOTCH4 gene promoter polymorphism is associated with the age of onset in schizophrenia.

Psychiatric genetics - 1 Jun 2003

Anttila Sami, Kampman Olli, Illi Ari, Roivas Markus, Mattila Kari M, Lassila Vesa, Lehtimäki Terho, Leinonen Esa

Abstract excerpt

OBJECTIVES: The NOTCH4 gene has a promoter polymor-phism at position -25, which leads to the three genotypes TT, CT and CC. These have been suggested to present a novel independent genetic risk factor for schizophrenia. We conducted a prospective case-control study to explore the impact of NOTCH4 T-25C polymorphism on the factors associated with schizophrenia. METHOD: NOTCH4 gene promoter T-25C polymorphism was...

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Source

Identifiers

PMID: 12782960
DOI: 10.1097/01.ypg.0000056681.82896.6b

Genes

NOTCH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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