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Article

Palmitoylation sites and processing of synaptotagmin I, the putative calcium sensor for neurosecretion.

FEBS letters - 5 Jun 2003

Heindel Ulrich, Schmidt Michael F G, Veit Michael

Abstract excerpt

Synaptotagmin I, the calcium sensor for neurotransmission, is palmitoylated. We have identified the palmitoylation sites as five cysteine residues located between the transmembrane and cytoplasmic regions. In contrast to wild-type synaptotagmin, the non-acylated mutant is not converted to the endoglycosidase-H-resistant form after expression in CV-1 cells. This indicates a block in transport through the Golgi...

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PMID: 12782290
DOI: 10.1016/s0014-5793(03)00449-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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