Article
The cysteine-string domain of the secretory vesicle cysteine-string protein is required for membrane targeting.
The Biochemical journal - 15 Oct 1998
Chamberlain L H, Burgoyne R D
Abstract excerpt
The post-translational addition of palmitic acid residues to cysteine-string protein (Csp) was originally thought to form the basis for membrane association of this secretory-vesicle protein. However, subsequent work showed that chemical depalmitoylation of Csp does not result in its release from membranes. We have confirmed these findings and employed [3H]palmitate labelling of PC12 cells to demonstrate that...
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