Article
Multiple palmitoylation of synaptotagmin and the t-SNARE SNAP-25.
FEBS letters - 29 Apr 1996
Veit M, Söllner T H, Rothman J E
Abstract excerpt
Synaptotagmin, a likely calcium sensor for synaptic transmission, and SNAP-25, a t-SNARE of the presynaptic plasma membrane, are key proteins for the docking and fusion of synaptic and other vesicles. We report that both synaptotagmin and SNAP-25 are palmitoylated with their fatty acids attached...
Topics
- Acylation
- Amino Acid Sequence
- Calcium-Binding Proteins
- Cell Fractionation
- Cell Membrane
- Cysteine
- Cytosol
- Membrane Glycoproteins
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Nerve Tissue Proteins
- Palmitic Acid
- Palmitic Acids
- Qa-SNARE Proteins
- Synaptosomal-Associated Protein 25
- Synaptotagmins