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Article

Differential effect of brefeldin A on the palmitoylation of surfactant protein C proprotein mutants.

Biochemical and biophysical research communications - 11 Jan 2002

ten Brinke Anja, Batenburg Joseph J, Haagsman Henk P, van Golde Lambert M G, Vaandrager Arie B

Abstract excerpt

The surfactant protein C precursor (proSP-C) is palmitoylated on two cysteines adjacent to its transmembrane domain. We showed previously that palmitoylation of proSP-C occurs in a postendoplasmic reticulum compartment and is not affected by the Golgi-disturbing agent brefeldin A (BFA). In contrast, the investigations presented here showed that BFA almost completely abolished palmitoylation of proSP-C mutants...

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Identifiers

PMID: 11779204
DOI: 10.1006/bbrc.2001.6223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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