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Article

Comparison of p53 mutational status with mRNA and protein expression in a panel of 24 human breast carcinoma cell lines.

Breast cancer research and treatment - 1 May 2003

Concin Nicole, Zeillinger Christa, Tong Dan, Stimpfl Margit, König Margit, Printz Dieter, Stonek Felix, Schneeberger Christian, Hefler Lukas, Kainz Christian, Leodolter Sepp, Haas Oskar A, Zeillinger Robert

Abstract excerpt

We analyzed the p53 mutational status, mRNA and protein expression in 24 human breast carcinoma cell lines. Following measurement of their DNA content with flow cytometry, we ascertained the copy numbers of the centromere of chromosome 17 (cen17) and p53 with fluorescence in situ hybridization (FISH). A functional yeast assay (FASAY) was used to screen for inactivating mutations. Positive results were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12779080
DOI: 10.1023/a:1023351717408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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