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Article

Prognostic significance of centromere 17 copy number gain in breast cancer depends on breast cancer subtype.

Human pathology - 1 Mar 2017

Lee Kyuongyul, Jang Min Hye, Chung Yul Ri, Lee Yangkyu, Kang Eunyoung, Kim Sung-Won, Kim Yu Jung, Kim Jee Hyun, Kim In Ah, Park So Yeon

Abstract excerpt

Increased copy number of chromosome enumeration probe (CEP) targeting centromere 17 is frequently encountered during HER2 in situ hybridization (ISH) in breast cancer. The aim of this study was to clarify the clinicopathologic significance of CEP17 copy number gain in a relatively large series of breast cancer patients. We analyzed 945 cases of invasive breast cancers whose HER2 fluorescence ISH reports were...

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Identifiers

PMID: 27989787
DOI: 10.1016/j.humpath.2016.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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