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Article

Thiopurine methyltransferase phenotypes and genotypes in Brazilians.

Pharmacogenetics - 1 Jun 2003

Reis Marcelo, Santoro Ana, Suarez-Kurtz Guilherme

Abstract excerpt

The polymorphism of thiopurine methyltransferase (TPMT) was studied in 306 healthy Brazilians who were classed, on the basis of self-declared colour and ancestry, as Euro-derived (n = 81), Afro-derived (n = 18) or having interethnic admixture (n = 204). TPMT activity (range 0.17-25.93 U) displayed a trimodal distribution of high (> 11.3 U; 9% of individuals), intermediate (5-11.3 U; 9.8%) and low (0.17 U; 0.3%)...

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Source

Identifiers

PMID: 12777968
DOI: 10.1097/00008571-200306000-00009

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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