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Article

Thiopurine methyltransferase polymorphisms in a Brazilian population.

The pharmacogenomics journal - 1 Jan 2003

Boson W L, Romano-Silva M A, Correa H, Falcão R P, Teixeira-Vidigal P V, De Marco L

Abstract excerpt

Thiopurine methyltransferase (TPMT) catalyses the S-methylation of thiopurine drugs. Low-activity phenotypes are correlated with several mutations in the TPMT gene. Polymorphisms of TPMT have been reported for Caucasians, African-Americans and Asians. Since ethnic differences have been demonstrat...

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Source

Identifiers

PMID: 12815366
DOI: 10.1038/sj.tpj.6500175

Genes

TPMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12815366-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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